Home > Product > Antibody > Rabbit Anti-NELL1/FITC Conjugated antibody
IDH3GL; NEL like protein 1; Nel related protein 1; NEL-like protein 1; Nel-related protein 1; Nell1; NELL1_HUMAN; Neural epidermal growth factor like 1; NRP1; Protein kinase C binding protein NELL1; Protein kinase C-binding protein NELL1.
Cat:
SL10704R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,Cow,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human NELL1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
87kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Function:
Involved in the control of cell growth and differentiation.

Subunit:
Homotrimer. Binds to PKC beta-1. Interacts with ATRAID; the interaction promotes osteoblast cell differentiation and mineralization.

Subcellular Location:
Secreted.

Similarity:
Contains 6 EGF-like domains.
Contains 1 TSP N-terminal (TSPN) domain.
Contains 5 VWFC domains.

Database links:

Entrez Gene: 4745 Human

Entrez Gene: 338352 Mouse

Entrez Gene: 81733 Rat

Omim: 602319 Human

SwissProt: Q92832 Human

SwissProt: Q2VWQ2 Mouse

SwissProt: Q62919 Rat

Unigene: 657172 Human

Unigene: 383528 Mouse

Unigene: 10695 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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