Rabbit Anti-NFS1/FITC Conjugated antibody

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Cysteine desulfurase; Cysteine desulfurase, mitochondrial; HUSSY 08; IscS; mitochondrial; NFS1; NFS1 nitrogen fixation 1; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NFS1_HUMAN; NIFS; nitrogen fixation 1 (S. cerevisiae, homolog); nitrogen

Cat:

SL19227R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from human NFS1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

50kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]

Function:
Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.

Subcellular Location:
Cytoplasm. Nucleus and Mitochondrion.

Tissue Specificity:
Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas.

Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

Database links:

Entrez Gene: 9054 Human

Entrez Gene: 3641 Mouse

Entrez Gene: 84594 Rat

Omim: 603485 Human

SwissProt: Q9Y697 Human

SwissProt: Q9Z1J3 Mouse

SwissProt: Q99P39 Rat

Unigene: 194692 Human

Unigene: 28724 Mouse

Unigene: 3151 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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