Rabbit Anti-HDGF/FITC Conjugated antibody

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HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2.

Cat:

SL10956R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from human HDGF

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

27kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.

Subunit:
Monomer, and domain-swapped homodimer.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.

Similarity:
Belongs to the HDGF family.
Contains 1 PWWP domain.

Database links:

Entrez Gene: 3068 Human

Entrez Gene: 15191 Mouse

Entrez Gene: 114499 Rat

Omim: 600339 Human

SwissProt: P51858 Human

SwissProt: P51859 Mouse

SwissProt: Q8VHK7 Rat

Unigene: 506748 Human

Unigene: 292208 Mouse

Unigene: 860 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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