Function:
May be a transcriptional repressor.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed at high levels in gastric glands, and at low levels in colon and small intestine. Silenced through promoter methylation in gastric glands with intestinal metaplasia.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 9 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Database links:
Entrez Gene: 284307 Human
Entrez Gene: 22775 Mouse
Entrez Gene: 690887 Rat
SwissProt: Q3SY52 Human
SwissProt: Q80YP6 Mouse
Unigene: 454830 Human
Unigene: 49441 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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