Rabbit Anti-NMD3/FITC Conjugated antibody

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60S ribosomal export protein NMD3; CGI 07; FLJ21053; hNMD3; NMD3 homolog; NMD3 homolog (S. cerevisiae).

Cat:

SL19288R-FITC

Species Reactivity：

Mouse,(predicted: Human,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human NMD3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

58kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1; MIM 602559) pathway (Trotta et al., 2003 [PubMed 12773398]).[supplied by OMIM, Mar 2008]

Function:
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.

Subunit:
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.

Subcellular Location:
Cytoplasm. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.

Similarity:
Belongs to the NMD3 family.

Database links:

Entrez Gene: 51068 Human

Entrez Gene: 509871 Cow

Entrez Gene: 488137 Dog

Entrez Gene: 97112 Mouse

Entrez Gene: 310512 Rat

Omim: 611021 Human

SwissProt: Q96D46 Human

SwissProt: Q99L48 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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