Home > Product > Antibody > Rabbit Anti-GRTP1/FITC Conjugated antibody
FLJ22474; Growth hormone-regulated TBC protein 1; Grtp1; GRTP1_HUMAN; MGC138328; MGC138330; OTTHUMP00000018752; TBC1 domain family member 6; TBC1 domain family, member 6; TBC1D6.
Cat:
SL20064R-FITC
Immunogen:
KLH conjugated synthetic peptide derived from human GRTP1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
39kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
GRTP1 is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events.

Function:
May act as a GTPase-activating protein for Rab family protein(s).

Similarity:
Contains 1 Rab-GAP TBC domain.

Database links:

Entrez Gene: 79774 Human

Entrez Gene: 66790 Mouse

Entrez Gene: 36236 Rat

SwissProt: Q5TC63 Human

SwissProt: Q9D3N8 Mouse

SwissProt: Q4QQU7 Rat

Unigene: 170904 Human

Unigene: 34901 Mouse

Unigene: 19589 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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