Home > Product > Antibody > Rabbit Anti-CACNG6/FITC Conjugated antibody
calcium channel voltage dependent gamma subunit 6; Neuronal voltage gated calcium channel gamma 6 subunit; Voltage-dependent calcium channel gamma-6 subunit.
Cat:
SL19636R-FITC
Immunogen:
KLH conjugated synthetic peptide derived from human CACNG6
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
28kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. [provided by RefSeq, Dec 2010]

Function:
Thought to stabilize the calcium channel in an inactivated (closed) state.

Subunit:
The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.

Subcellular Location:
Plasma membrane

Similarity:
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

Database links:

Entrez Gene: 59285 Human

Entrez Gene: 54378 Mouse

Entrez Gene: 140727 Rat

Omim: 606898 Human

SwissProt: Q9BXT2 Human

SwissProt: Q8VHW3 Mouse

SwissProt: Q8VHW7 Rat

Unigene: 91033 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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