Rabbit Anti-SDPR/FITC Conjugated antibody

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Cavin 2; Cavin-2; Phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS p68; PS-p68; Sdpr; SDPR_HUMAN; SDR; Serum deprivation response; Serum deprivation response protein; Serum deprivation-response protein.

Cat:

SL19605R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human SDPR

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

47kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Function:
May play a role in targeting PRKCA to caveolae.

Subcellular Location:
Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae.

Tissue Specificity:
Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.

Post-translational modifications:
Phosphorylated on Ser residues.

Similarity:
Belongs to the PTRF/SDPR family.

Database links:

Entrez Gene: 8436 Human

Entrez Gene: 20324 Mouse

Entrez Gene: 316384 Rat

Omim: 606728 Human

SwissProt: O95810 Human

SwissProt: Q63918 Mouse

SwissProt: Q66H98 Rat

Unigene: 26530 Human

Unigene: 96575 Mouse

Unigene: 203035 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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