Rabbit Anti-PSMG2/HCCA3/FITC Conjugated antibody

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CD40 ligand activated specific transcript 3; CLAST3; HCCA3; Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-susceptibility protein 3; HSPC260; HsT1707; Likely ortholog of mouse CD40 ligand activated specific transcript 3;

Cat:

SL19578R-FITC

Species Reactivity：

(predicted: Human,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human PSMG2/HCCA3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

29kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue.

Post-translational modifications:
Degraded by the proteasome upon completion of 20S proteasome maturation.

Similarity:
Belongs to the PSMG2 family.

Database links:

Entrez Gene: 56984 Human

Entrez Gene: 533993 Cow

Entrez Gene: 107047 Mouse

Entrez Gene: 291539 Rat

Omim: 609702 Human

SwissProt: Q2NL24 Cow

SwissProt: Q969U7 Human

SwissProt: Q9EST4 Mouse

Unigene: 464652 Human

Unigene: 150701 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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