Home > Product > Antibody > Rabbit Anti-NSUN5P2/FITC Conjugated antibody
FLJ11626; MGC129801; MGC15057; NOL1/NOP2/Sun domain family member 5C; NOL1R2; NOP2/Sun domain family, member 5 pseudogene 2; NOP2/Sun domain family, member 5C (pseudogene); NOP2/Sun domain family, member 5C; NSUN5C; Putative methyltransferase NSU
Cat:
SL19483R-FITC
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human NSUN5P2
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
34kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
This locus represents a transcribed pseudogene of a nearby locus on chromosome 7, which encodes a putative methyltransferase. There is also a third closely related pseudogene locus in this region. There is extensive alternative splicing at this locus. [provided by RefSeq, Jul 2013]

Function:
May have S-adenosyl-L-methionine-dependent methyl-transferase activity.

Tissue Specificity:
Ubiquitous.

DISEASE:
NSUN5C is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.

Similarity:
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Database links:

Entrez Gene: 260294 Human

SwissProt: Q63ZY6 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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