Rabbit Anti-SFMBT1/FITC Conjugated antibody

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DKFZp434L243; MGC93349; OTTMUSP00000030378; OTTMUSP00000030379; OTTMUSP00000030381; Renal ubiquitous protein 1; RU1; Scm like with four mbt domains 1; Scm like with four MBT domains protein 1; Scm related gene containing four mbt domains; Scm re

Cat:

SL19682R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human SFMBT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

98kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]

Function:
Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.

Tissue Specificity:
Expressed in all cell lines and normal tissues tested, including the thymus.

Similarity:
Contains 4 MBT repeats.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 5192 Human

Entrez Gene: 54650 Mouse

Entrez Gene: 58967 Rat

Omim: 607319 Human

SwissProt: Q9UHJ3 Human

SwissProt: Q9JMD1 Mouse

SwissProt: Q9JMD2 Rat

Unigene: 343679 Human

Unigene: 294662 Mouse

Unigene: 14839 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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