Rabbit Anti-SLC39A4/FITC Conjugated antibody

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1600025H15Rik; Acrodermatitis enteropathica zinc deficiency type; Activated in W/Wv mouse stomach 2; AEZ; AU041686; AWMS2; FLJ20327; MGC156705; MGC74741; S39A4_HUMAN; Slc39a4; Solute carrier family 39 member 4; Ssolute carrier family 39 zinc t

Cat:

SL19832R-FITC

Species Reactivity：

Human,Rat,

Immunogen：

KLH conjugated synthetic peptide derived from human SLC39A4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

66kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Function:
Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.

Subcellular Location:
Cell membrane. Recycling endosome membrane. Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.

Tissue Specificity:
Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.

DISEASE:
Acrodermatitis enteropathica, zinc-deficiency type (AEZ)

Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.

Database links:

Entrez Gene: 55630 Human

Entrez Gene: 72027 Mouse

Omim: 607059 Human

SwissProt: Q6P5W5 Human

SwissProt: Q78IQ7 Mouse

Unigene: 521934 Human

Unigene: 276829 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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