background:
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to USLVSLCinduced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
Function:
3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily
Subcellular Location:
Mitochondrion and Nucleus.
Similarity:
Belongs to the oligoribonuclease family.
Contains 1 exonuclease domain.
Database links:
Entrez Gene: 25996 Human
Entrez Gene: 540139 Human
Omim: 607149 Human
SwissProt: Q9Y3B8 Human
Unigene: 677190 Human
Unigene: 714231 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|
