Rabbit Anti-PARVA/FITC Conjugated antibody

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Actopaxin; Alpha parvin; Alpha-parvin; Calponin like integrin linked kinase binding protein; Calponin-like integrin-linked kinase-binding protein; CH ILKBP; CH-ILKBP; FLJ10793; FLJ12254; Matrix remodelling associated 2; Matrix remodelling associ

Cat:

SL19892R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human PARVA

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

42kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Function:
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis.

Subcellular Location:
Cell junction > focal adhesion. Cell membrane. Cytoplasm > cytoskeleton. Constituent of focal adhesions.

Tissue Specificity:
Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.

Similarity:
Belongs to the parvin family.
Contains 2 CH (calponin-homology) domains.

Database links:

Entrez Gene: 55742 Human

Entrez Gene: 57342 Mouse

Entrez Gene: 57341 Rat

Omim: 608120 Human

SwissProt: Q9NVD7 Human

SwissProt: Q9EPC1 Mouse

SwissProt: Q9HB97 Rat

Unigene: 432914 Human

Unigene: 143763 Mouse

Unigene: 92564 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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