Rabbit Anti-PARP14/FITC Conjugated antibody

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ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; BAL2; Collaborator of STAT6; KIAA1268; PAR14_HUMAN; PARP 14; PARP-14; PARP14; pART8; Poly (ADP ribose) polymerase family member 14; Poly [ADP-ribose] polym

Cat:

SL19886R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PARP14

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

203kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).[supplied by OMIM, Mar 2008]

Function:
Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.

Subunit:
Interacts with STAT6.

Subcellular Location:
Nucleus. Cytoplasm. In steady state cells the protein is mostly nuclear. A minor proportion is detected in the cytoplasm.

Similarity:
Contains 3 Macro domains.
Contains 1 PARP catalytic domain.
Contains 1 WWE domain.

Database links:

Entrez Gene: 54625 Human

Entrez Gene: 547253 Mouse

Entrez Gene: 303903 Rat

Omim: 610028 Human

SwissProt: Q92N5 Human

SwissProt: Q2EMV9 Mouse

Unigene: 518203 Human

Unigene: 24886 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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