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Rabbit Anti-PCTAIRE1/FITC Conjugated antibody
background:
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]
Function:
May play a role in signal transduction cascades in terminally differentiated cells.
Subunit:
Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Interacts with NSF.Identified in a complex with NSF, syntaxin-1, synaptotagmin, SYN1,SYP and CDK5R1 (By similarity). Interacts with BRSK2. Interacts with CCNY; this increases the CDK16 kinase activity.
Subcellular Location:
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side.Cell junction, synapse, synaptosome
Similarity:
Belongs to the protein kinase superfamily.
CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Contains 1 protein kinase domain.
Database links:
Entrez Gene: 613810 Cow
Entrez Gene: 5127 Human
Entrez Gene: 18555 Mouse
Omim: 311550 Human
SwissProt: Q00536 Human
SwissProt: Q04735 Mouse
Unigene: 496068 Human
Unigene: 102574 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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