background:
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]
Function:
Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo.
Subcellular Location:
Cytoplasm. Nucleus.
Tissue Specificity:
Ovary, testis and peripheral blood leukocytes.
Similarity:
Belongs to the protein arginine deiminase family.
Database links:
Entrez Gene: 353238 Human
Omim: 610363 Human
SwissProt: Q6TGC4 Human
Unigene: 531598 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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