Rabbit Anti-SLD5/FITC Conjugated antibody

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DNA replication complex GINS protein SLD5; GINS complex subunit 4 (Sld5 homolog); GINS complex subunit 4; GINS4; SLD5; SLD5 homolog; SLD5 S cerevisiae homolog of; SLD5_HUMAN.

Cat:

SL21031R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SLD5

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

26kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]

Function:
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the GINS4/SLD5 family.

Database links:

Entrez Gene: 770899 Chicken

Entrez Gene: 482843 Dog

Entrez Gene: 100055757 Horse

Entrez Gene: 84296 Human

Entrez Gene: 109145 Mouse

Entrez Gene: 100738105 Pig

Entrez Gene: 290842 Rat

Entrez Gene: 703350 Rhesus monkey

Entrez Gene: 572562 Zebrafish

Omim: 610611 Human

SwissProt: Q9BRT9 Human

SwissProt: Q99LZ3 Mouse

SwissProt: Q499W2 Rat

Unigene: 656996 Human

Unigene: 27945 Mouse

Unigene: 103411 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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