Function:
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
Subcellular Location:
Cytoplasm. Endosome membrane. Interaction with PIP5K3 and subsequent phosphorylation recruits it to the endosomal membrane.
Post-translational modifications:
Phosphorylated on Ser residues most probably by PIP5K3.
Similarity:
Contains 5 Kelch repeats.
Database links:
Entrez Gene: 10244 Human
Entrez Gene: 227746 Mouse
Entrez Gene: 296649 Rat
Omim: 605962 Human
SwissProt: Q7Z6M1 Human
SwissProt: Q8VCH5 Mouse
SwissProt: Q4V8F4 Rat
Unigene: 19012 Human
Unigene: 158705 Mouse
Unigene: 436837 Mouse
Unigene: 39139 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|