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Rabbit Anti-p39/CDK5R2/FITC Conjugated antibody
background:
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]
Function:
Activator of CDK5/TPKII.
Subunit:
Heterodimer of a catalytic subunit and a regulatory subunit.
Tissue Specificity:
Brain and neuron specific.
Post-translational modifications:
Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39).
Similarity:
Belongs to the cyclin-dependent kinase 5 activator family.
Database links:
Entrez Gene: 8941 Human
Entrez Gene: 12570 Mouse
Omim: 603764 Human
SwissProt: Q13319 Human
SwissProt: O35926 Mouse
Unigene: 15892 Human
Unigene: 153833 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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