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Rabbit Anti-PPEF1/FITC Conjugated antibody
background:
This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008]
Function:
May have a role in the recovery or adaptation response of photoreceptors. May have a role in development.
Tissue Specificity:
Detected in retina and retinal derived Y-79 retinoblastoma cells. Also found in fetal brain.
Similarity:
Belongs to the PPP phosphatase family.
Contains 3 EF-hand domains.
Contains 1 IQ domain.
Database links:
Entrez Gene: 5475 Human
Omim: 300109 Human
SwissProt: O14829 Human
Unigene: 211589 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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