Rabbit Anti-PFDN3/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-PFDN3/FITC Conjugated antibody

HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1; Von Hippel-Lindau-binding protein 1.

Cat:

SL12628R-FITC

Species Reactivity：

Human,Mouse,

Immunogen：

KLH conjugated synthetic peptide derived from human PFDN3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

23kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]

Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Subcellular Location:
Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the prefoldin subunit alpha family.

Database links:

Entrez Gene: 508727 Cow

Entrez Gene: 481089 Dog

Entrez Gene: 7411 Human

Entrez Gene: 22327 Mouse

Omim: 300133 Human

SwissProt: Q2TBX2 Cow

SwissProt: P61758 Human

SwissProt: P61759 Mouse

Unigene: 47363 Human

Unigene: 8294 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall