Rabbit Anti-SNAPC5/FITC Conjugated antibody

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Small nuclear RNA activating complex polypeptide 5 19kDa; Small nuclear RNA activating complex polypeptide 5; SNAP 19; SNAP19; SNAPc 19 kDa subunit; SNAPC 5; SNAPc subunit 5; snRNA activating protein complex 19 kDa subunit; snRNA activating protei

Cat:

SL12651R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SNAPC5

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

11kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
SNAPC5 is a subunit of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC5 binds to the proximal sequence element (PSE) common to the promotor regions of these 2 types of genes, and recruits TBP and BRF2 to the U6 snRNA TATA box.

Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

Subunit:
Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC5 interacts with SNAPC4.1 Publication.

Subcellular Location:
Nuclear.

Database links:

Entrez Gene: 10302 Human

Entrez Gene: 330959 Mouse

Entrez Gene: 691501 Rat

Omim: 605979 Human

SwissProt: O75971 Human

SwissProt: Q8R2K7 Mouse

Unigene: 30174 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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