Rabbit Anti-SNAP47/FITC Conjugated antibody

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C1orf142; Chromosome 1 open reading frame 142; FLJ12517; HEL170; OTTHUMP00000035832; SNAP 47; SVAP1; Synaptosomal associated protein, 47kDa; t SNARE coiled coil homology domain containing protein C1orf142.

Cat:

SL12650R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SNAP47

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

52kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
SNAP47 belongs to the SVAP1 family. It contains two t-SNARE coiled-coil homology domains. SNAP47 has ubiquitous tissue distribution, with particularly high levels in nervous tissue. In neurons, SNAP 47 has been shown to have widespread distribution on intracellular membranes and is enriched in synaptic vesicle fractions. In vitro, SNAP 47 can substitute for SNAP-25 in SNARE complex formation, but not as efficiently.

Function:
Plays a role in intracellular membrane fusion.

Subunit:
Forms a complex containing SNAP47, VAMP2 and STX1A (By similarity). Associates with the BLOSLC1 complex. Interacts with BLOC1S6.

Subcellular Location:
Endomembrane system. Cytoplasm; perinuclear region. Note: Appears to be exclusively membrane-bound.

Similarity:
Belongs to the SVAP1 family.
Contains 2 t-SNARE coiled-coil homology domains.

Database links:

Entrez Gene: 116841 Human

Entrez Gene: 67826 Mouse

Entrez Gene: 303183 Rat

SwissProt: Q5SQN1 Human

SwissProt: Q8R570 Mouse

SwissProt: Q6P6S0 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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