Rabbit Anti-ValRS/FITC Conjugated antibody

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Bat 6; Bat6; D17H6S56E; EC 6.1.1.9; G7A; Protein G7a; SYVC_HUMAN; valine tRNA ligase 1, cytoplasmic; Valine tRNA ligase; Valine--tRNA ligase; ValRS; VALYL tRNA SYNTHETASE 1; valyl tRNA synthetase 2; valyl-tRNA synthetase 2; Valyl-tRNA synthe

Cat:

SL1536R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Danio)

Immunogen：

KLH conjugated synthetic peptide derived from human ValRS

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

140kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

DISEASE:
The disease is caused by mutations affecting the gene represented in this entry.
Disease description:A disorder due to mitochondrial respiratory chain complex defects. Clinical features are variable and include muscle weakness with hypotonia, central neurological disease with progressive external ophthalmoplegia, ptosis and ataxia, delayed psychomotor development, cardiomyopathy, abnormal liver function, facial dysmorphism, microcephaly and epilepsy.

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.
Contains 1 GST SLCterminal domain.

Database links:

Entrez Gene: 7407 Human

Entrez Gene: 22321 Mouse

Entrez Gene: 25009 Rat

Omim: 192150 Human

SwissProt: P26128 Human

SwissProt: Q9Z1Q9 Mouse

SwissProt: Q04462 Rat

Unigene: 520026 Human

Unigene: 28420 Mouse

Unigene: 12314 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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