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Rabbit Anti-TMPRSS11D/FITC Conjugated antibody
background:
This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]
Function:
May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Subcellular Location:
Secreted. Activated by cleavage and secreted and Cell membrane. Activated by cleavage and secreted.
Tissue Specificity:
Located in the cells of the submucosal serous glands of the bronchi and trachea.
Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain.
Database links:
Entrez Gene: 9407 Human
Omim: 605369 Human
SwissProt: O60235 Human
Unigene: 132195 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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