Rabbit Anti-PNRC2/FITC Conjugated antibody

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0610011E17Rik; D4Bwg0593e; FLJ20312; MGC11707; MGC93828; MGC99541; OTTMUSP00000010360; OTTMUSP00000010366; pnrc2; PNRC2_HUMAN; Proline rich nuclear receptor coactivator 2; Proline-rich nuclear receptor coactivator 2; RP11-4M23.5; RP23-161N17.

Cat:

SL12748R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human PNRC2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

16kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.

Subcellular Location:
Nucleus. Cytoplasm > P-body.

Tissue Specificity:
Expressed in heart, lung, muscle and brain.

Similarity:
Belongs to the PNRC family. PNRC2 subfamily.

Database links:

Entrez Gene: 100505603 Human

Entrez Gene: 55629 Human

Entrez Gene: 52830 Mouse

Entrez Gene: 100125373 Rat

Omim: 611882 Human

SwissProt: Q9NPJ4 Human

SwissProt: Q9CR73 Mouse

SwissProt: Q66HE1 Rat

Unigene: 512636 Human

Unigene: 644217 Human

Unigene: 716935 Human

Unigene: 7862 Human

Unigene: 29159 Mouse

Unigene: 118788 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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