Rabbit Anti-PLVAP/FITC Conjugated antibody

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FELS; Fenestrated endothelial linked structure protein; Fenestrated endothelial-linked structure protein; gp68; Hypothetical protein DKFZp667O074; Meca 32 antigen; MECA32 antigen; Panendothelial cell antigen; Plasmalemma vesicle associated protein

Cat:

SL12737R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Dog,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PLVAP

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

50kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
PLVAP (Plasmalemma Vesicle Associated Protein) is a Protein Coding gene. Diseases associated with PLVAP include Breast Benign Neoplasm and Thoracic Benign Neoplasm. GO annotations related to this gene include protein homodimerization activity.

Function:
Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.

Subcellular Location:
Cell membrane. Membrane > caveola. Cytoplasm > perinuclear region. Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region.

Tissue Specificity:
Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium.

Database links:

Entrez Gene: 83483 Human

Omim: 607647 Human

SwissProt: Q9BX97 Human

Unigene: 107125 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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