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Rabbit Anti-VRK2/FITC Conjugated antibody
background:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]
Function:
Probable serine/threonine kinase.
Subcellular Location:
Membrane.
Tissue Specificity:
Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis.
Similarity:
Belongs to the protein kinase superfamily.
CK1 Ser/Thr protein kinase family.
VRK subfamily.
Contains 1 protein kinase domain.
Database links:
Entrez Gene: 7444 Human
Entrez Gene: 69922 Mouse
Omim: 602169 Human
SwissProt: Q86Y07 Human
SwissProt: Q8BN21 Mouse
Unigene: 728198 Human
Unigene: 285351 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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