Home > Product > Antibody > Rabbit Anti-VRK2/FITC Conjugated antibody
2810003O05Rik; AI447698; EC 2.7.11.1; Serine/threonine protein kinase VRK2; Serine/threonine-protein kinase VRK2; Vaccinia related kinase 2; Vaccinia virus B1R related kinase 2; Vaccinia-related kinase 2; VRK 2; VRK2; VRK2_HUMAN.
Cat:
SL12780R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,Chicken,)
Immunogen:
KLH conjugated synthetic peptide derived from human VRK2
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
58kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]

Function:
Probable serine/threonine kinase.

Subcellular Location:
Membrane.

Tissue Specificity:
Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis.

Similarity:
Belongs to the protein kinase superfamily.
CK1 Ser/Thr protein kinase family.
VRK subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 7444 Human

Entrez Gene: 69922 Mouse

Omim: 602169 Human

SwissProt: Q86Y07 Human

SwissProt: Q8BN21 Mouse

Unigene: 728198 Human

Unigene: 285351 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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