Rabbit Anti-VPS41/FITC Conjugated antibody

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HVPS41; hVps41p; HVSP41; S53; Vacuolar assembly protein 41; Vacuolar protein sorting 41 (yeast homolog); Vacuolar protein sorting 41 (yeast); Vacuolar protein sorting 41 homolog (S. cerevisiae); Vacuolar protein sorting associated protein 41 homol

Cat:

SL12776R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from human VPS41

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

96kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]

Function:
Required for vacuolar assembly and vacuolar traffic.

Subcellular Location:
Cytoplasmic face of coated pits and vesicles.

Similarity:
Belongs to the VPS41 family.
Contains 1 CHCR (clathrin heavy-chain) repeat.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 420762 Chicken

Entrez Gene: 528654 Cow

Entrez Gene: 27072 Human

Entrez Gene: 23635 Mouse

Entrez Gene: 306991 Rat

Omim: 605485 Human

SwissProt: P49754 Human

SwissProt: Q5KU39 Mouse

Unigene: 592184 Human

Unigene: 27389 Mouse

Unigene: 1289 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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