Rabbit Anti-VPS37C/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-VPS37C/FITC Conjugated antibody

5730409F24Rik; AU042646; ESCRT I complex subunit VPS37C; ESCRT-I complex subunit VPS37C; FLJ20847; hVps37C; PML39; RGD1309258; Vacuolar protein sorting 37 homolog C (S. cerevisiae); Vacuolar protein sorting 37C (yeast); Vacuolar protein sorting

Cat:

SL12774R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human VPS37C

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

39kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]

Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

Subcellular Location:
Late endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HISLV1.

Similarity:
Belongs to the VPS37 family.
Contains 1 VPS37 SLCterminal domain.

Database links:

Entrez Gene: 55048 Human

Entrez Gene: 107305 Mouse

Entrez Gene: 308178 Rat

Omim: 610038 Human

SwissProt: A5D8V6 Human

SwissProt: Q8R105 Mouse

Unigene: 523715 Human

Unigene: 19091 Mouse

Unigene: 12915 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall