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Rabbit Anti-ZNF197/FITC Conjugated antibody
background:
This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nuclear
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 22 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Contains 1 SCAN box domain.
Database links:
Entrez Gene: 515564 Cow
Entrez Gene: 10168 Human
SwissProt: O14709 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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