Rabbit Anti-ZNF703/FITC Conjugated antibody

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FLJ14299; ZEPPO1; Zinc finger elbow-related proline domain protein 1; Zinc finger protein 703; ZN703_HUMAN; ZNF503L; znf703; ZPO1.

Cat:

SL20145R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF703

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

58kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.

Subcellular Location:
Nucleus. Cytoplasm

Tissue Specificity:
Expressed in mammary epithelium.

DISEASE:
Amplification of the gene correlates with its protein expression in tumor cells. ZNF703 is a classical breast cancer oncogene since it is able to transform non-malignant cells and increase cellular proliferation.

Similarity:
Belongs to the Elbow/Noc family.
Contains 1 C2H2-type zinc finger.

Database links:

Entrez Gene: 80139 Human

Entrez Gene: 353310 Mouse

Entrez Gene: 136717 Rat

SwissProt: Q9H7S9 Human

SwissProt: P0CL69 Mouse

Unigene: 726062 Human

Unigene: 212469 Mouse

Unigene: 15384 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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