Rabbit Anti-ZNF139/FITC Conjugated antibody

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9130423L19Rik; KOX18; MGC138429; MGC63357; OTTHUMP00000210080; PHZ 37; PHZ-37; Zinc finger protein 139; Zinc finger protein 36 (KOX 18); Zinc finger protein 36; Zinc finger protein KOX18; Zinc finger protein with KRAB and SCAN domains 1; ZKSC1

Cat:

SL7154R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF139

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

64kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010]

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 6 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Contains 1 SCAN box domain.

Database links:

Entrez Gene: 7586 Human

Entrez Gene: 74570 Mouse

Entrez Gene: 498160 Rat

Omim: 601260 Human

SwissProt: P17029 Human

SwissProt: Q8BGS3 Mouse

SwissProt: Q4KLI1 Rat

Unigene: 61572 Human

Unigene: 213114 Mouse

Unigene: 113295 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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