Home
>
Product
>
Antibody
>
Rabbit Anti-ZMIZ2/FITC Conjugated antibody
background:
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]
Function:
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.
Subcellular Location:
Nucleus. Detected at replication foci throughout S phase.
Tissue Specificity:
Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary.
Similarity:
Contains 1 SP-RING-type zinc finger.
Database links:
Entrez Gene: 83637 Human
Entrez Gene: 52915 Mouse
Entrez Gene: 289783 Rat
Entrez Gene: 6378 Rat
Omim: 611196 Human
SwissProt: Q8NF64 Human
SwissProt: Q8CIE2 Mouse
Unigene: 600681 Human
Unigene: 77978 Human
Unigene: 1144 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|