Rabbit Anti-SCY1 like 3/FITC Conjugated antibody

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Ezrin binding protein PACE 1; Ezrin-binding protein PACE-1; PACE 1; PACE1; PACE1_HUMAN; Protein associating with the carboxyl terminal domain of ezrin; Protein-associating with the carboxyl-terminal domain of ezrin; SCY1 like 3 (S. cerevisiae); SC

Cat:

SL8696R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SCY1 like 3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

82kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the SLCterminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]

Function:
May play a role in regulating cell adhesion/migration complexes in migrating cells.

Subcellular Location:
Cytoplasm. Golgi apparatus. Cell projection > lamellipodium. Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
May be myristoylated; myristoylation may target it to Golgi compartment. Phosphorylated.

Similarity:
Belongs to the protein kinase superfamily.
Contains 4 HEAT repeats.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 57147 Human

Omim: 608192 Human

SwissProt: Q8IZE3 Human

Unigene: 435560 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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