Rabbit Anti-RALGPS2/FITC Conjugated antibody

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dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2.

Cat:

SL21178R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human RALGPS2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

65kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain.

Function:
Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).

Subunit:
Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA.

Subcellular Location:
Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain.

DISEASE:
RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24.

Database links:

Entrez Gene: 424429 Chicken

Entrez Gene: 457549 Chimpanzee

Entrez Gene: 100052879 Horse

Entrez Gene: 55103 Human

Entrez Gene: 78255 Mouse

Entrez Gene: 304887 Rat

Entrez Gene: 717165 Rhesus monkey

Entrez Gene: 779506 Xenopus tropicalis

Entrez Gene: 393446 Zebrafish

SwissProt: Q5ZJK0 Chicken

SwissProt: Q4R7W3 Cynomolgus Monkey

SwissProt: Q86X27 Human

SwissProt: Q9ERD6 Mouse

Unigene: 632485 Human

Unigene: 28376 Mouse

Unigene: 224486 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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