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Rabbit Anti-RALGPS1/FITC Conjugated antibody
background:
May be involved in cytoskeletal organization (By similarity). May also be involved in the stimulation of transcription in a Ras independent fashion (By similarity). Guanine nucleotide exchange factor for the small GTPase RALA. Six different isoforms have been described.
Function:
Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for.
Subunit:
Interacts with the SH3 domains of GRB2, NCK1, PLCG1 and SRC.
Subcellular Location:
Cell Membrane and Cytoplasmic.
Tissue Specificity:
Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus.
Database links:
Entrez Gene: 9649 Human
SwissProt: Q5JS13 Human
Unigene: 648175 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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