background:
SGSM3 (Small G Protein Signaling Modulator 3) is a Protein Coding gene. GO annotations related to this gene include GTPase activator activity and Rab GTPase binding. An important paralog of this gene is TBC1D30.
Function:
May play a cooperative role in NF2-mediated growth suppression of cells.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the small G protein signaling modulator family.
Contains 1 Rab-GAP TBC domain.
Contains 1 RUN domain.
Contains 1 SH3 domain.
Database links:
Entrez Gene: 27352 Human
Entrez Gene: 105835 Mouse
Entrez Gene: 362963 Rat
Omim: 61088 Human
SwissProt: Q96HU1 Human
SwissProt: Q8VCZ6 Mouse
SwissProt: Q6P6R7 Rat
Unigene: 474914 Human
Unigene: 274943 Mouse
Unigene: 66996 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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