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Rabbit Anti-SHISA5/FITC Conjugated antibody
background:
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Function:
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
Subunit:
Interacts with PDCD6; PDCD6 can stabilze SHISA5.
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.
DISEASE:
Induced in a p53/TP53-dependent manner in response to cellular stress
Database links:
Entrez Gene: 51246 Human
Omim: 607290 Human
SwissProt: Q8N114 Human
Unigene: 414579 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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