background:
SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Li et al., 2004). This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 1356753]).[supplied by OMIM, Mar 2008]
Function:
High-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose.
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed in small intestine and colon. Weakly expressed in testis and prostate.
Similarity:
Belongs to the major facilitator superfamily.
Sugar transporter (TC 2.A.1.1) family.
Glucose transporter subfamily.
Database links:
Entrez Gene: 155184 Human
Omim: 610371 Human
SwissProt: Q6PXP3 Human
Unigene: 531239 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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