Rabbit Anti-RBM15B/FITC Conjugated antibody

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1810017N16Rik; Chromosome 3p21.1 gene sequence; HUMAGCGB; huOTT3; One twenty two protein 3; One-twenty two protein 3; OTT3; Putative RNA binding protein 15B; Putative RNA-binding protein 15B; RB15B_HUMAN; RBM15B; RGD1305937; RNA binding motif

Cat:

SL21289R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human RBM15B

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

97kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

Function:
May function in the regulation of alternative or illicit splicing.

Subcellular Location:
Nucleus > nucleoplasm. Colocalizes with BMLF1 in the nucleus. Localized in the nucleoplasm with a granular staining pattern and excluded from the nucleoli.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the RRM Spen family.
Contains 3 RRM (RNA recognition motif) domains.
Contains 1 SPOC domain.

Database links:

Entrez Gene: 29890 Human

Entrez Gene: 109095 Mouse

Entrez Gene: 315988 Rat

Omim: 612602 Human

SwissProt: Q8NDT2 Human

SwissProt: Q6PHZ5 Mouse

Unigene: 118738 Human

Unigene: 431589 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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