Rabbit Anti-ZNF143/FITC Conjugated antibody

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MGC66276; mStaf; pHZ 1; SBF; Selenocysteine tRNA gene transcription activating factor; SPH binding factor; STAF; Zfp143; zgc:66276; Zinc finger protein 143.

Cat:

SL20535R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF143

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

69kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
ZNF143 is a human homolog of Xenopus transcriptional activator staf that is involved in selenocystyl tRNA transcription which binds to the SPH motif of small nuclear RNA (snRNA) gene promoters.

Function:
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.

Subunit:
Interacts with CHD8.

Subcellular Location:
Nuclear.

Tissue Specificity:
Expressed in all tissues tested, with the strongest expression in ovary.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family. Contains 7 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7702 Human

Omim: 603433 Human

SwissProt: P52747 Human

SwissProt: O70230 Mouse

SwissProt: Q5XIU2 Rat

Unigene: 523471 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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