background:
Annexin A8 like 2 is a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The protein may function as an anticoagulant that indirectly inhibits the thromboplastin-specific complex, and overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
Function:
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Similarity:
Belongs to the annexin family.
Contains 4 annexin repeats.
Database links:
Entrez Gene: 244 Human
Entrez Gene: 653145 Human
Entrez Gene: 11752 Mouse
Entrez Gene: 306283 Rat
Omim: 602396 Human
SwissProt: P13928 Human
SwissProt: O35128 Mouse
SwissProt: Q4FZU6 Rat
Unigene: 535306 Human
Unigene: 705389 Human
Unigene: 3267 Mouse
Unigene: 104326 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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