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Rabbit Anti-Peroxiredoxin-4/FITC Conjugated antibody
background:
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]
Function:
Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
Subcellular Location:
Cytoplasm. Secreted.
Similarity:
Belongs to the ahpC/TSA family.
Contains 1 thioredoxin domain.
Database links:
Entrez Gene: 281999 Cow
Entrez Gene: 10549 Human
Entrez Gene: 53381 Mouse
Entrez Gene: 85274 Rat
Omim: 606506 Human
SwissProt: Q9BGI2 Cow
SwissProt: Q13162 Human
SwissProt: O01767 Mouse
SwissProt: Q9Z0V5 Rat
Unigene: 83383 Human
Unigene: 247542 Mouse
Unigene: 17958 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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