Home > Product > Antibody > Mouse Anti-Bovine Serum Albumin/FITC Conjugated antibody
ALB; Bovine Serum Albumin; Albumin; Allergen Bos d 6; BSA; Serum albumin; ALBU_BOVIN.
Cat:
SLM3641M-FITC
Species Reactivity:
Cow,
Immunogen:
Purified BSA Protein
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Monoclonal
Isotype:
IgG
Applications:
not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Mouse
Calculated MW:
66kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].

Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma.

Post-translational modifications:
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.

DISEASE:
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:10720]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

Similarity:
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.

Database links:
Entrez Gene: 280717 Cow

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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