Mouse Anti-RAB18/FITC Conjugated antibody

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RAB18; RAB18 member RAS oncogene family; RAB18 small GTPase; RAB18_HUMAN; RAB18LI1; Ras-related protein Rab-18.

Cat:

SLM51333M-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

Recombinant human RAB18 protein

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Monoclonal

Isotype：

IgG1

Applications：

not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Mouse

Calculated MW：

23kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 22931 Human

Entrez Gene: 19330 Mouse

Entrez Gene: 307039 Rat

Omim: 602207 Human

SwissProt: Q9NP72 Human

SwissProt: P35293 Mouse

SwissProt: Q5EB77 Rat

Unigene: 406799 Human

Unigene: 132802 Mouse

Unigene: 472772 Mouse

Unigene: 53248 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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