[IF=2.952] Linyan Cheng. et al. Icariin attenuates thioacetamide‑induced bone loss via the RANKL‑p38/ERK‑NFAT signaling pathway. Mol Med Rep. 2022 Apr;25(4):1-11 WB ; Rat.
[IF=4.36] Hong Zhao. et al. Protective effect of flavonoids extract of Hippophae rhamnoides L. on alcoholic fatty liver disease through regulating intestinal flora and inhibiting TAK1/p38MAPK/p65NF-κB pathway. J Ethnopharmacol. 2022 Jun;292:115225 WB ; Mouse.
[IF=4.55] Ning, Chong, et al. "Chicory inulin ameliorates type 2 diabetes mellitus and suppresses JNK and MAPK pathways in vivo and in vitro." Molecular Nutrition & Food Research (2017). WB ; Rat.
[IF=3.118] Jiang Y et al. Changes in inflammatory factors and protein expression in sulfur mustard (1LD 50)-induced acute pulmonary injury in rats.International Immunopharmacology, 2018 61, 338–345. IHSLCP ; Rat.
[IF=2.448] Ji X et al. Double-component diazeniumdiolate derivatives as anti-cancer agents. Bioorg Med Chem. 2020 Apr 15;28(8):115405. WB ; human.
[IF=4.165] Shenjie Zhong. et al. Bmp8a is an essential positive regulator of antiviral immunity in zebrafish. Commun Biol. 2021 Mar;4(1):1-15 WB ; Zebrafish.
[IF=3.412] Tianqing Huang. et al. Screening and Validation of p38 MAPK Involved in Ovarian Development of Brachymystax lenok. Front Vet Sci. 2022; 9: 752521 WB ; Fish(Lenok).
[IF=12.91] Kuo-Chu Lai. et al. IFIT2-depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice. 2022 Feb 15 WB ; Mouse.
[IF=5.455] Zhang, Rongrong. et al. Compound traditional Chinese medicine dermatitis ointment ameliorates inflammatory responses and dysregulation of itch-related molecules in atopic dermatitis. Chin Med-Uk. 2022 Dec;17(1):1-19 WB ; Mouse.
[IF=5.923] Junfeng Ke. et al. CTI-2 Inhibits Metastasis and Epithelial-Mesenchymal Transition of Breast Cancer Cells by Modulating MAPK Signaling Pathway. Int J Mol Sci. 2021 Jan;22(22):12229 WB,IF ; Human.
[IF=4.36] Yue Shen. et al. Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways. J Ethnopharmacol. 2022 Feb;284:114791 WB ; Human.
[IF=4.171] Yan Zhang. et al. Polysaccharide from Ganoderma lucidum ameliorates cognitive impairment by regulating the inflammation of the brain–liver axis in rats. 2021 May 18 WB ; Rat.
[IF=1.837] Yang Zhang. et al. Plumbagin Inhibits Proliferation, Migration, and Invasion of Retinal Pigment Epithelial Cells Induced by FGF-2. Tissue Cell. 2021 Oct;72:101547 WB ; Human.
[IF=2.1] Le Zhuang. et al. Evaluation of the effects of IL‑22 on the proliferation and differentiation of keratinocytes in vitro. Mol Med Rep. 2020 Oct;22(4):2715-2722 WB ; Human.
[IF=3.641] Wenbo Ge. et al. 17β-estradiol protects sheep oviduct epithelial cells against lipopolysaccharide-induced inflammation in vitro. Mol Immunol. 2020 Nov;127:21 WB ; Sheep.
[IF=2.245] Pengwei Wang. et al. Deoxynivalenol Induces Inflammation in the Small Intestine of Weaned Rabbits by Activating Mitogen-Activated Protein Kinase Signaling. Front Vet Sci. 2021; 8: 632599 WB,IHC ; Rabbit.
[IF=6.551] Shuming Chen. et al. Melamine induces reproductive dysfunction via down-regulated the phosphorylation of p38 and downstream transcription factors Max and Sap1a in mice testes. Sci Total Environ. 2021 May;770:144727 WB ; Mouse.
[IF=3.216] Chao Lu. et al. Inhibition of Pre-B Cell Colony Enhancing Factor Reduces Lung Injury in Rats Receiving Cardiopulmonary Bypass. Drug Des Dev Ther. 2021; 15: 51–60 WB ; Rat.
[IF=2.205] Liu A et al. Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathwaysBioengineered.2021 Dec;12(1):183-195. WB ; Mouse.
[IF=2.868] Liu B et al. MicroRNA‐379 mediates pigmentation, migration, and proliferation of melanocytes by targeting the insulin‐like growth factor 1 receptor. Exp Dermatol. 2020 May;29(5):467-476. WB ; alpaca.
[IF=1.719] Zhou J et al. Paeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway. Acta Histochem. 2019 Oct 3:151455. WB ; Mouse&Human.
[IF=3.266] Ma Q et al. Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation. Am J Transl Res. 2019 Aug 15;11(8):5008-5018. eCollection 2019. WB ; Mouse.
[IF=3.06] Li T et al. Withanolides, extracted from Datura metel L. inhibit keratinocyte proliferation and imiquimod- induced psoriasis-like dermatitis via the STAT3/P38/ERK1/2 pathway. Molecules. 2019 Jul 17;24(14). pii: E2596. WB ; Human.
[IF=2.394] Liu W et al. Synergistic effect of tolfenamic acid and glycyrrhizic acid on TPA-induced skin inflammation in mice. MedChemComm.2019. IHSLCP ; Mouse.
[IF=5.614] Zhu J et al. SPARC Promotes Self‐Renewal of Limbal Epithelial Stem Cells and Ocular Surface Restoration through JNK and p38‐MAPK Signaling Pathways. Stem Cells. 2019 Oct 23. WB ; Rabbit.
[IF=4.868] Wang G et al. Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blockingthe TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response. Oxid Med Cell Longev. 2019 Apr 28;2019:7850324. WB ; Mouse.
[IF=2.553] Liu W et al. Suppressive effect of glycyrrhizic acid against lipopolysaccharide-induced neuroinflammation and cognitive impairment in C57 mice via toll-like receptor 4 signaling pathway. Food Nutr Res. 2019 Apr 29;63. IHC ; Mouse.
[IF=0] Ola-Davies OE et al. Ameliorative effects of Annona muricata Linn. (Annonaceae) against potassium dichromate-induced hypertension in vivo: involvement of Kim-1/p38 MAPK/Nrf2 signaling. J Basic Clin Physiol Pharmacol. 2019 May 3. IHSLCP ; Rat.
[IF=3.118] Fu S et al. Berberine suppresses mast cell-mediated allergic responses via regulating FcɛRI-mediated and MAPK signaling.Int Immunopharmacol. 2019 Jun;71:1-6. WB ; Human.
[IF=4.61] Yue H et al. Gestational exposure to PM2.5 impairs vascularization of the placenta. Sci Total Environ. 2019 May 15;665:153-161. WB ; Mouse.
[IF=3.098] Fan Y et al. S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells.(2018) Molecules 23(12) WB ; Human.
[IF=3.038] Oyagbemi AA et al. Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways. (2018) Sep 02 IHC ; Rat.
[IF=2.342] Liu W et al. Glycyrrhizic acid from licorice down-regulates inflammatory responses via blocking MAPK and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation. MedChemComm. 2018. IHSLCP ; Mouse.
[IF=2.25] Gao W et al. The combination of indirubin and isatin attenuates dextran sodium sulfate induced ulcerative colitis in mice.Biochem Cell Biol. 2018 Oct;96(5):636-645. WB ; Mouse.
[IF=1.173] Jin B et al. Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway. Exp Anim. 2018 Jul 30;67(3):337-347. WB ; Rat.
[IF=0] Wang et al. Upregulation of progranulin by Helicobacter pylori in human gastric epithelial cells via p38MAPK and MEK1/2 signaling pathway: role in epithelial cell proliferation and migration. (2011) FEMS.Immunol.Med.Microbiol. 63:82-92 WB ; Human.
[IF=1.922] Cao et al. Dickkopf‑3 upregulation mediates the cardioprotective effects of curcumin on chronic heart failure. (2018) Mol.Med.Rep. 17:7249-7257 WB ; rabbit.
[IF=1.39] Li et al. Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells. (2017) Oncol.Lett. 14:4751-4757 WB ; Human.
[IF=1.26] Zhao et al. Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damagein vivoandin vitro. (2017) Exp.Ther.Med. 14:5515-5522 WB ; Human.
[IF=1.2] Zhao, Dongmei, et al. "Unfractionated heparin protects the protein C system against lipopolysaccharide‑induced damage in vivo and in vitro." Experimental and Therapeutic Medicine. WB ; Human.
[IF=1.69] Liu, Xinwei, et al. "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." Molecular Medicine Reports 16.1 (2017): 192-200. WB ; Rat.
[IF=4.42] Yu, Haijie, et al. "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." Frontiers in Pharmacology 7 (2016). WB ; Rat.
[IF=2.27] Yu, Wu, et al. "BEX4 upregulation alters Sertoli cell growth properties and protein expression profiles: An explanation for cadmium‐induced testicular Sertoli cell injury." Journal of Biochemical and Molecular Toxicology (2017).
[IF=2.38] Cong, Lin, and Wenting Chen. "Neuroprotective Effect of Ginsenoside Rd on Spinal Cord Injury Rats." Basic & Clinical Pharmacology & Toxicology(2016). WB ; Rat.
[IF=1.75] Shi, Zeyu, et al. "Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice." Biological Trace Element Research (2016): 1-6. WB ; Mouse.
[IF=0.23] Wang, B., et al. "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." Neural Regeneration Research 9.18 (2014): 1678. WB ; Rat.
[IF=2.97] Li, Lingrui, et al. "Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling." Chemico-Biological Interactions (2013). WB ; Human.
[IF=1.894] Gong et al. Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4)-Mediated Signaling. (2018) Med.Sci.Monit. 24:3514-3523 IHC,WB ; human.
[IF=2.136] Zhao Z et al. BMP15 regulates AMH expression via the p38 MAPK pathway in granulosa cells from goat.Theriogenology. 2018 Sep 15;118:72-79. WB ; Goat.
[IF=4.011] Zhou C et al. Combining transcatheter arterial embolization with iodized oil containing Apatinib inhibits HCC growth and metastasis. Sci Rep. 2020 Feb 19;10(1):2964. WB ; Human.
[IF=5.156] Li, Muzhe. et al. Effects of adenovirus-mediated knockdown of IRAK4 on synovitis in the osteoarthritis rabbit model. Arthritis Res Ther. 2021 Dec;23(1):1-12 WB ; Rabbits.
[IF=3.738] Lili Liu. et al. Rutin Ameliorates Cadmium-Induced Necroptosis in the Chicken Liver via Inhibiting Oxidative Stress and MAPK/NF-κB Pathway. 2021 Jun 06 WB ; Chicken.
[IF=2.447] Mei-Hua Jin. et al. Hispidin inhibits LPS‑induced nitric oxide production in BV‑2 microglial cells via ROS‑dependent MAPK signaling. Exp Ther Med. 2021 Sep;22(3):1-9 WB ; Mouse.
[IF=2.245] Dahan Yang. et al. Tandem Mass Tag-Based Quantitative Proteomic Analysis of Chicken Bursa of Fabricius Infected With Reticuloendotheliosis Virus. Front Vet Sci. 2021; 8: 666512 WB ; Chicken.
[IF=4.087] Paola Pietrangeli. et al. Lathyrus sativus diamine oxidase reduces Clostridium difficile toxin A‐induced toxicity in Caco‐2 cells by rescuing RhoA‐GTPase and inhibiting pp38‐MAPK/NF‐κB/HIF‐1α activation. Phytother Res. 2021 Jan;35(1):415-423 WB ; Human.
[IF=4.486] Shun Huang. et al. Design, Synthesis, and Activity Study of Cinnamic Acid Derivatives as Potent Antineuroinflammatory Agents. Acs Chem Neurosci. 2021;12(3):419–429 WB ; Mouse.