Rabbit Anti-G3BP2 antibody | Sunlong Medical

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G3BP 2; G3BP-2; G3BP2; G3BP2_HUMAN; GAP SH3 domain binding protein 2; GAP SH3 domain-binding protein 2; GTPase activating protein (SH3 domain) binding protein 2; Ras GTPase activating protein SH3 domain binding protein 2; Ras GTPase-activating protein-bin

Cat:

SL13252R

Species Reactivity：

Mouse,Rat,(predicted: Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human G3BP2:21-120/482

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Heart (Rat) Lysate at 40 ug Primary: Anti-G3BP2 (SL13252R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD Sample: Cerebrum (Mouse) Lysate at 40 ugPrimary: Anti-G3BP2 (SL13252R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 54 kDObserved band size: 54 kDSample: Brain (Mouse) Lysate at 40 ugCerebellum (Mouse) Lysate at 40 ugPrimary: Anti-G3BP2 (SL13252R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 54 kDObserved band size: 54 kDSample: Bone (Mouse) Lysate at 40 ugPrimary: Anti-G3BP2 (SL13252R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 54 kDObserved band size: 54 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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G3BP2 (GTPase activating protein (SH3 domain) binding protein 2) is a 482 amino acid protein that localizes to the cytoplasm and contains one NTF2 domain and one RRM domain. Existing as two alternatively spliced isoforms, G3BP2 acts as a scaffold protein that is thought to be involved in mRNA transport and is subject to post-translational methylation on select arginine residues. The gene encoding G3BP2 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Function:
Probable scaffold protein that may be involved in mRNA transport.

Subunit:
Binds to the N-terminal domain of I-kappa-B-alpha.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Arg-457 and Arg-468 are dimethylated, probably to asymmetric dimethylarginine.

Similarity:
Contains 1 NTF2 domain.
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q9UN86

Gene ID:
9908

Database links:

Entrez Gene: 9908 Human

Entrez Gene: 23881 Mouse

Entrez Gene: 30548 Rat

SwissProt: Q9UN86 Human

SwissProt: P97379 Mouse

SwissProt: Q5R9L3 Orangutan

Unigene: 303676 Human

Unigene: 290530 Mouse

Unigene: 473827 Mouse

Picture

Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-G3BP2 (SL13252R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD

Sample:
Brain (Mouse) Lysate at 40 ug
Cerebellum (Mouse) Lysate at 40 ug
Primary: Anti-G3BP2 (SL13252R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD

Sample:
Bone (Mouse) Lysate at 40 ug
Primary: Anti-G3BP2 (SL13252R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD

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