Home > Product > Antibody > Rabbit Anti-Thymosin Alpha-1 antibody
Prothymosin alpha (gene sequence 28); Prothymosin alpha; Prothymosin alpha like 1 protein; Thymalfasin; Thymosin alpha 1 acetate; Thymosin alpha 1; Thymosin alpha; TMSA; PTMA; PTMA_HUMAN.
Cat:
SL0226R
Species Reactivity:
Human,Rat,(predicted: Mouse,Cow,)
Immunogen:
KLH conjugated synthetic peptide derived from human Thymosin Alpha-1:2-29/111
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, SLC0005) at 37°C for 20 min; Antibody incubation with (Thymosin Alpha-1) polyclonal Antibody, Unconjugated (SL0026R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
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Product PDFs
Datasheet:


The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin alpha. A peptide containing 28 amino acid residues, named thymosin alpha 1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and in vivo test systems. Thymosin alpha 1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin alpha 1.

Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

Subcellular Location:
Nucleus.

Post-translational modifications:
Covalently linked to a small RNA of about 20 nucleotides.

Similarity:
Belongs to the pro/parathymosin family.

SWISS:
P06454

Gene ID:
5757

Database links:

Entrez Gene: 5757 Human

Omim: 188390 Human

SwissProt: P06454 Human

Unigene: 459927 Human

Unigene: 708083 Human



胸腺素α-1;胸腺肽 Picture

MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, SLC0005) at 37°C for 20 min; Antibody incubation with (Thymosin Alpha-1) polyclonal Antibody, Unconjugated (SL0026R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
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